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Genetic determinants of dengue type 4 virus neurovirulence for mice.

Mouse-adapted dengue type 4 virus (DEN4) strain H241 is highly neurovirulent for mice, whereas its non-mouse-adapted parent is rarely neurovirulent. The genetic basis for the neurovirulence of the mouse-adapted mutant was studied by comparing intratypic chimeric viruses that contained the three stru...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Kawano, H, Rostapshov, V, Rosen, L, Lai, C J
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238094/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8411360/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.11.6567-6575.1993
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