An Essential Role for IFN-γ in Regulation of Alloreactive CD8 T Cells Following Allogeneic Hematopoietic Cell Transplantation

We have previously shown that CD8 T cells from IFN-γ gene knockout (GKO) donors induces more severe lethal graft-vs.-host disease (GVHD) compared to CD8 T cells from wild type (WT) donors in fully MHC-mismatched strain combinations. In this study, we investigated the mechanisms by which IFN-γ inhibi...

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Bibliografiske detaljer
Main Authors: Asavaroengchai, Wannee, Wang, Hui, Wang, Shumei, Wang, Lan, Bronson, Roderick, Sykes, Megan, Yang, Yong-Guang
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1893089/
https://ncbi.nlm.nih.gov/pubmed/17222752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2006.09.014
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