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An Essential Role for IFN-γ in Regulation of Alloreactive CD8 T Cells Following Allogeneic Hematopoietic Cell Transplantation
We have previously shown that CD8 T cells from IFN-γ gene knockout (GKO) donors induces more severe lethal graft-vs.-host disease (GVHD) compared to CD8 T cells from wild type (WT) donors in fully MHC-mismatched strain combinations. In this study, we investigated the mechanisms by which IFN-γ inhibi...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1893089/ https://ncbi.nlm.nih.gov/pubmed/17222752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2006.09.014 |
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