Deletion of CASK in mice is lethal and impairs synaptic function

CASK is an evolutionarily conserved multidomain protein composed of an N-terminal Ca(2+)/calmodulin-kinase domain, central PDZ and SH3 domains, and a C-terminal guanylate kinase domain. Many potential activities for CASK have been suggested, including functions in scaffolding the synapse, in organiz...

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Detalhes bibliográficos
Main Authors: Atasoy, Deniz, Schoch, Susanne, Ho, Angela, Nadasy, Krisztina A., Liu, Xinran, Zhang, Weiqi, Mukherjee, Konark, Nosyreva, Elena D., Fernandez-Chacon, Rafael, Missler, Markus, Kavalali, Ege T., Südhof, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892970/
https://ncbi.nlm.nih.gov/pubmed/17287346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611003104
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