Lewy Body Pathology in Familial Alzheimer Disease: Evidence for Disease- and Mutation-Specific Pathologic Phenotype

BACKGROUND: The origin and significance of Lewy bodies and neurites (Lewy body pathology [LBP]) in Alzheimer disease (AD) are poorly understood. OBJECTIVE: To examine LBP in the brainstem, limbic cortex, and neocortex of a large number of familial AD cases with mutations in 2 presenilin (PSEN) genes...

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Autori principali: Leverenz, James B., Fishel, Mark A., Peskind, Elaine R., Montine, Thomas J., Nochlin, David, Steinbart, Ellen, Raskind, Murray A., Schellenberg, Gerard D., Bird, Thomas D., Tsuang, Debby
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892620/
https://ncbi.nlm.nih.gov/pubmed/16533963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneur.63.3.370
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