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Cell-Type-Specific Repression of the Maspin Gene Is Disrupted Frequently by Demethylation at the Promoter Region in Gastric Intestinal Metaplasia and Cancer Cells

Maspin, a serine protease inhibitor, was originally reported as a tumor suppressor gene in breast and prostatic cancers. We examined maspin expression and/or the allele-specific methylation status in four gastric cancer cell lines, as well as normal, metaplastic, and cancerous epithelia obtained fro...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Akiyama, Yuji, Maesawa, Chihaya, Ogasawara, Satoshi, Terashima, Masanori, Masuda, Tomoyuki
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Investigative Pathology 2003
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892440/
https://ncbi.nlm.nih.gov/pubmed/14578190
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