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Primary Gastric Carcinoma Cells Frequently Lose Heterozygosity at the APC and MCC Genetic Loci

Loss of heterozygosity (LOH) at APC and MCC gene loci (both mapped to 5q21) was investigated in 24 surgical specimens of primary gastric carcinomas using the polymerase chain reaction after tumor cell enrichment by cell sorting based on differences in DNA content. LOH at APC and/or MCC was detected...

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Dettagli Bibliografici
Pubblicato in:Jpn J Cancer Res
Autori principali: Tamura, Gen, Maesawa, Chihaya, Suzuki, Yasushi, Ogasawara, Satoshi, Terashima, Masanori, Saito, Kazuyoshi, Satodate, Ryoichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 1993
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919060/
https://ncbi.nlm.nih.gov/pubmed/8226275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1993.tb02794.x
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