Cell-Type-Specific Repression of the Maspin Gene Is Disrupted Frequently by Demethylation at the Promoter Region in Gastric Intestinal Metaplasia and Cancer Cells

Maspin, a serine protease inhibitor, was originally reported as a tumor suppressor gene in breast and prostatic cancers. We examined maspin expression and/or the allele-specific methylation status in four gastric cancer cell lines, as well as normal, metaplastic, and cancerous epithelia obtained fro...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Akiyama, Yuji, Maesawa, Chihaya, Ogasawara, Satoshi, Terashima, Masanori, Masuda, Tomoyuki
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Investigative Pathology 2003
الموضوعات:
Regular Articles
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892440/
https://ncbi.nlm.nih.gov/pubmed/14578190
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