Implications of Glucose Transporter Protein Type 1 (GLUT1)-Haplodeficiency in Embryonic Stem Cells for Their Survival in Response to Hypoxic Stress

Glucose transporter protein type 1 (GLUT1) is a major glucose transporter of the fertilized egg and preimplantation embryo. Haploinsufficiency for GLUT1 causes the GLUT1 deficiency syndrome in humans, however the embryo appears unaffected. Therefore, here we produced heterozygous GLUT1 knockout muri...

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Bibliografiske detaljer
Main Authors: Heilig, Charles, Brosius, Frank, Siu, Brian, Concepcion, Luis, Mortensen, Richard, Heilig, Kathleen, Zhu, Min, Weldon, Richard, Wu, Guimei, Conner, David
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2003
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892427/
https://ncbi.nlm.nih.gov/pubmed/14578187
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