Implications of Glucose Transporter Protein Type 1 (GLUT1)-Haplodeficiency in Embryonic Stem Cells for Their Survival in Response to Hypoxic Stress

Glucose transporter protein type 1 (GLUT1) is a major glucose transporter of the fertilized egg and preimplantation embryo. Haploinsufficiency for GLUT1 causes the GLUT1 deficiency syndrome in humans, however the embryo appears unaffected. Therefore, here we produced heterozygous GLUT1 knockout muri...

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Main Authors: Heilig, Charles, Brosius, Frank, Siu, Brian, Concepcion, Luis, Mortensen, Richard, Heilig, Kathleen, Zhu, Min, Weldon, Richard, Wu, Guimei, Conner, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
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Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892427/
https://ncbi.nlm.nih.gov/pubmed/14578187
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