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Implications of Glucose Transporter Protein Type 1 (GLUT1)-Haplodeficiency in Embryonic Stem Cells for Their Survival in Response to Hypoxic Stress

Glucose transporter protein type 1 (GLUT1) is a major glucose transporter of the fertilized egg and preimplantation embryo. Haploinsufficiency for GLUT1 causes the GLUT1 deficiency syndrome in humans, however the embryo appears unaffected. Therefore, here we produced heterozygous GLUT1 knockout muri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Heilig, Charles, Brosius, Frank, Siu, Brian, Concepcion, Luis, Mortensen, Richard, Heilig, Kathleen, Zhu, Min, Weldon, Richard, Wu, Guimei, Conner, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892427/
https://ncbi.nlm.nih.gov/pubmed/14578187
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