The Inhibitory Receptor FcγRII Reduces Joint Inflammation and Destruction in Experimental Immune Complex-Mediated Arthritides Not Only by Inhibition of FcγRI/III but Also by Efficient Clearance and Endocytosis of Immune Complexes

Studies of FcγRII−/− mice identified the inhibitory function of this receptor in joint inflammation and cartilage destruction induced with immune complexes (ICs). To extend our insight in the role of FcγRII in arthritis, we explored the role of FcγRII in the absence of activating receptors I and III...

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Hlavní autoři: van Lent, Peter, Nabbe, Karin C., Boross, Peter, Blom, Arjen B., Roth, Johannes, Holthuysen, Astrid, Sloetjes, Annet, Verbeek, Sjef, van den Berg, Wim
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2003
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892415/
https://ncbi.nlm.nih.gov/pubmed/14578184
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