The Inhibitory Receptor FcγRII Reduces Joint Inflammation and Destruction in Experimental Immune Complex-Mediated Arthritides Not Only by Inhibition of FcγRI/III but Also by Efficient Clearance and Endocytosis of Immune Complexes

Studies of FcγRII−/− mice identified the inhibitory function of this receptor in joint inflammation and cartilage destruction induced with immune complexes (ICs). To extend our insight in the role of FcγRII in arthritis, we explored the role of FcγRII in the absence of activating receptors I and III...

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Autors principals: van Lent, Peter, Nabbe, Karin C., Boross, Peter, Blom, Arjen B., Roth, Johannes, Holthuysen, Astrid, Sloetjes, Annet, Verbeek, Sjef, van den Berg, Wim
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2003
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Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892415/
https://ncbi.nlm.nih.gov/pubmed/14578184
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