Alterations of β-Catenin Pathway in Non-Melanoma Skin Tumors : Loss of α-ABC Nuclear Reactivity Correlates with the Presence of β-Catenin Gene Mutation

To determine the role of β-catenin pathway in human skin carcinogenesis, 135 non-melanoma skin tumors were analyzed for β-catenin expression and gene mutations. Intense nucleo-cytoplasmic immunoreactivity for C terminus β-catenin antibodies was observed in all pilomatricomas and in single cases of t...

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Bibliografiske detaljer
Main Authors: Doglioni, Claudio, Piccinin, Sara, Demontis, Silvia, Cangi, Maria Giulia, Pecciarini, Lorenza, Chiarelli, Concetta, Armellin, Michela, Vukosavljevic, Tamara, Boiocchi, Mauro, Maestro, Roberta
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2003
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892405/
https://ncbi.nlm.nih.gov/pubmed/14633602
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