An improved sequencing-based strategy to estimate locus-specific DNA methylation

BACKGROUND: DNA methylation is an important epigenetic mechanism of transcriptional control that plays an essential role in several cellular functions. Aberrant DNA methylation in cancer has been frequently associated with downregulation of microRNAs and protein coding genes, such as miR-200c/miR-14...

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Bibliografski detalji
Izdano u:BMC Cancer
Glavni autori: Brisotto, Giulia, di Gennaro, Alessandra, Damiano, Valentina, Armellin, Michela, Perin, Tiziana, Maestro, Roberta, Santarosa, Manuela
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Technical Advance
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578270/
https://ncbi.nlm.nih.gov/pubmed/26391005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1646-6
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