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An improved sequencing-based strategy to estimate locus-specific DNA methylation
BACKGROUND: DNA methylation is an important epigenetic mechanism of transcriptional control that plays an essential role in several cellular functions. Aberrant DNA methylation in cancer has been frequently associated with downregulation of microRNAs and protein coding genes, such as miR-200c/miR-14...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | BMC Cancer |
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Κύριοι συγγραφείς: | , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
BioMed Central
2015
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4578270/ https://ncbi.nlm.nih.gov/pubmed/26391005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1646-6 |
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