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An improved sequencing-based strategy to estimate locus-specific DNA methylation

BACKGROUND: DNA methylation is an important epigenetic mechanism of transcriptional control that plays an essential role in several cellular functions. Aberrant DNA methylation in cancer has been frequently associated with downregulation of microRNAs and protein coding genes, such as miR-200c/miR-14...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Brisotto, Giulia, di Gennaro, Alessandra, Damiano, Valentina, Armellin, Michela, Perin, Tiziana, Maestro, Roberta, Santarosa, Manuela
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578270/
https://ncbi.nlm.nih.gov/pubmed/26391005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1646-6
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