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Multiple solutions to inefficient lesion bypass by T7 DNA polymerase
We hypothesize that enzymatic switching during translesion synthesis (TLS) to relieve stalled replication forks occurs during transitions from preferential to disfavored use of damaged primer–templates, and that the polymerase or 3′-exonuclease used for each successive nucleotide incorporated is the...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1892196/ https://ncbi.nlm.nih.gov/pubmed/16876489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2006.06.003 |
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