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A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand binding sites

BACKGROUND: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will lead to improved methods for protein-ligand docking and binding site analysis. Most current shape descriptors characterize...

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Bibliographic Details
Main Authors: Xie, Lei, Bourne, Philip E
Format: Artigo
Language:Inglês
Published: BioMed Central 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892088/
https://ncbi.nlm.nih.gov/pubmed/17570152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-S4-S9
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