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Predicting target-ligand interactions using protein ligand-binding site and ligand substructures

BACKGROUND: Cell proliferation, differentiation, Gene expression, metabolism, immunization and signal transduction require the participation of ligands and targets. It is a great challenge to identify rules governing molecular recognition between chemical topological substructures of ligands and the...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Wang, Caihua, Liu, Juan, Luo, Fei, Deng, Zixing, Hu, Qian-Nan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331677/
https://ncbi.nlm.nih.gov/pubmed/25707321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-9-S1-S2
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