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Constrained hidden Markov models for population-based haplotyping

BACKGROUND: Haplotype Reconstruction is the problem of resolving the hidden phase information in genotype data obtained from laboratory measurements. Solving this problem is an important intermediate step in gene association studies, which seek to uncover the genetic basis of complex diseases. We pr...

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Detalhes bibliográficos
Main Authors: Landwehr, Niels, Mielikäinen, Taneli, Eronen, Lauri, Toivonen, Hannu, Mannila, Heikki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892078/
https://ncbi.nlm.nih.gov/pubmed/17493258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-S2-S9
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