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Constrained hidden Markov models for population-based haplotyping

BACKGROUND: Haplotype Reconstruction is the problem of resolving the hidden phase information in genotype data obtained from laboratory measurements. Solving this problem is an important intermediate step in gene association studies, which seek to uncover the genetic basis of complex diseases. We pr...

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Bibliografische gegevens
Hoofdauteurs: Landwehr, Niels, Mielikäinen, Taneli, Eronen, Lauri, Toivonen, Hannu, Mannila, Heikki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892078/
https://ncbi.nlm.nih.gov/pubmed/17493258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-S2-S9
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