Constrained hidden Markov models for population-based haplotyping

BACKGROUND: Haplotype Reconstruction is the problem of resolving the hidden phase information in genotype data obtained from laboratory measurements. Solving this problem is an important intermediate step in gene association studies, which seek to uncover the genetic basis of complex diseases. We pr...

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Bibliographic Details
Main Authors: Landwehr, Niels, Mielikäinen, Taneli, Eronen, Lauri, Toivonen, Hannu, Mannila, Heikki
Format: Artigo
Language:Inglês
Published: BioMed Central 2007
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892078/
https://ncbi.nlm.nih.gov/pubmed/17493258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-S2-S9
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