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Relocalization of Apoptosis-Inducing Factor in Photoreceptor Apoptosis Induced by Retinal Detachment in Vivo

Apoptosis-inducing factor (AIF) is a novel mediator in apoptosis. AIF is a flavoprotein that is normally confined to the mitochondrial intermembrane space, yet translocates to the nucleus in several in vitro models of apoptosis. To investigate the role of AIF in the apoptotic process in vivo, we ind...

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Detalhes bibliográficos
Main Authors: Hisatomi, Toshio, Sakamoto, Taiji, Murata, Toshinori, Yamanaka, Ichiro, Oshima, Yuji, Hata, Yasuaki, Ishibashi, Tatsuro, Inomata, Hajime, Susin, Santos A., Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891920/
https://ncbi.nlm.nih.gov/pubmed/11290545
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