Effects on XIAP Retinal Detachment–Induced Photoreceptor Apoptosis

PURPOSE: To evaluate the ability of X-linked inhibitor of apoptosis (XIAP) gene therapy to provide neuroprotection to cells of the outer nuclear layer (ONL) of the retina after retinal detachment. METHODS: Subretinal injections of a recombinant adenoassociated virus (rAAV) encoding either XIAP or gr...

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Main Authors: Zadro-Lamoureux, Laura A., Zacks, David N., Baker, Adam N., Zheng, Qiong-Duan, Hauswirth, William W., Tsilfidis, Catherine
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715305/
https://ncbi.nlm.nih.gov/pubmed/19060276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2855
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