Reprogramming leukemic cells to terminal differentiation by inhibiting specific cyclin-dependent kinases in G(1)
Some tumor cells can be stimulated to differentiate and undergo terminal cell division and loss of tumorigenicity. The in vitro differentiation of murine erythroleukemia (MEL) cells is a dramatic example of tumor-cell reprogramming. We found that reentry of MEL cells into terminal differentiation is...
محفوظ في:
| الحاوية / القاعدة: | Proc Natl Acad Sci U S A |
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| المؤلفون الرئيسيون: | , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
National Academy of Sciences
2000
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18916/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11114185/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.250488697 |
| الوسوم: |
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