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Construction of a genome-scale structural map at single-nucleotide resolution

Few methods are available for mapping the local structure of DNA throughout a genome. The hydroxyl radical cleavage pattern is a measure of the local variation in solvent-accessible surface area of duplex DNA, and thus provides information on the local shape and structure of DNA. We report the const...

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Dettagli Bibliografici
Autori principali: Greenbaum, Jason A., Pang, Bo, Tullius, Thomas D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891353/
https://ncbi.nlm.nih.gov/pubmed/17568010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6073107
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