Nick-seq for single-nucleotide resolution genomic maps of DNA modifications and damage

DNA damage and epigenetic marks are well established to have profound influences on genome stability and cell phenotype, yet there are few technologies to obtain high-resolution genomic maps of the many types of chemical modifications of DNA. Here we present Nick-seq for quantitative, sensitive, and...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Cao, Bo, Wu, Xiaolin, Zhou, Jieliang, Wu, Hang, Liu, Lili, Zhang, Qinghua, DeMott, Michael S, Gu, Chen, Wang, Lianrong, You, Delin, Dedon, Peter C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337925/
https://ncbi.nlm.nih.gov/pubmed/32484547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa473
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