Nick-seq for single-nucleotide resolution genomic maps of DNA modifications and damage

DNA damage and epigenetic marks are well established to have profound influences on genome stability and cell phenotype, yet there are few technologies to obtain high-resolution genomic maps of the many types of chemical modifications of DNA. Here we present Nick-seq for quantitative, sensitive, and...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Cao, Bo, Wu, Xiaolin, Zhou, Jieliang, Wu, Hang, Liu, Lili, Zhang, Qinghua, DeMott, Michael S, Gu, Chen, Wang, Lianrong, You, Delin, Dedon, Peter C
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
Materias:
Genomics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337925/
https://ncbi.nlm.nih.gov/pubmed/32484547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa473
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