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Cyclin D–Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization
Endomitosis is a unique form of cell cycle used by megakaryocytes, in which the latter stages of mitosis are bypassed so that the cell can increase its DNA content and size. Although several transcription factors, including GATA-1 and RUNX-1, have been implicated in this process, the link between tr...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Hematology
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1890844/ https://ncbi.nlm.nih.gov/pubmed/17317855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-11-059378 |
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