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Pph3–Psy2 is a phosphatase complex required for Rad53 dephosphorylation and replication fork restart during recovery from DNA damage

Activation of the checkpoint kinase Rad53 is a critical response to DNA damage that results in stabilization of stalled replication forks, inhibition of late-origin initiation, up-regulation of dNTP levels, and delayed entry to mitosis. Activation of Rad53 is well understood and involves phosphoryla...

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Bibliografske podrobnosti
Main Authors: O'Neill, Bryan M., Szyjka, Shawn J., Lis, Ewa T., Bailey, Aaron O., Yates, John R., Aparicio, Oscar M., Romesberg, Floyd E.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890487/
https://ncbi.nlm.nih.gov/pubmed/17517611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703252104
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