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Single-molecule force spectroscopy reveals a mechanically stable protein fold and the rational tuning of its mechanical stability

It is recognized that shear topology of two directly connected force-bearing terminal β-strands is a common feature among the vast majority of mechanically stable proteins known so far. However, these proteins belong to only two distinct protein folds, Ig-like β sandwich fold and β-grasp fold, signi...

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Hlavní autoři: Sharma, Deepak, Perisic, Ognjen, Peng, Qing, Cao, Yi, Lam, Canaan, Lu, Hui, Li, Hongbin
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890485/
https://ncbi.nlm.nih.gov/pubmed/17517616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700351104
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