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The helix–turn–helix motif as an ultrafast independently folding domain: The pathway of folding of Engrailed homeodomain
Helices 2 and 3 of Engrailed homeodomain (EnHD) form a helix–turn–helix (HTH) motif. This common motif is believed not to fold independently, which is the characteristic feature of a motif rather than a domain. But we found that the EnHD HTH motif is monomeric and folded in solution, having essentia...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1890484/ https://ncbi.nlm.nih.gov/pubmed/17517666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703434104 |
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