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Relating destabilizing regions to known functional sites in proteins

BACKGROUND: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relatives. Another limitation of these methods is the lack of a well annotated set of functional sites to use as benchmark for va...

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Detalhes bibliográficos
Main Authors: Dessailly, Benoît H, Lensink, Marc F, Wodak, Shoshana J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890302/
https://ncbi.nlm.nih.gov/pubmed/17470296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-141
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