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Deciphering the folding kinetics of transmembrane helical proteins

Nearly a quarter of genomic sequences and almost half of all receptors that are likely to be targets for drug design are integral membrane proteins. Understanding the detailed mechanisms of the folding of membrane proteins is a largely unsolved, key problem in structural biology. Here, we introduce...

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Bibliografische gegevens
Hoofdauteurs: Orlandini, Enzo, Seno, Flavio, Banavar, Jayanth R., Laio, Alessandro, Maritan, Amos
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC18900/
https://ncbi.nlm.nih.gov/pubmed/11121029
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