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Common attributes of native-state structures of proteins, disordered proteins, and amyloid

We show that a framework derived from the common character of globular proteins can be used to understand the design of protein sequences, the behavior of intrinsically unstructured proteins, and the formation of amyloid fibrils in a unified manner. Our studies provide compelling support for the ide...

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Detalhes bibliográficos
Main Authors: Hoang, Trinh X., Marsella, Luca, Trovato, Antonio, Seno, Flavio, Banavar, Jayanth R., Maritan, Amos
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458988/
https://ncbi.nlm.nih.gov/pubmed/16624879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601824103
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