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Size of genetic bottlenecks leading to virus fitness loss is determined by mean initial population fitness.

Genetic bottlenecks are important events in the genetic diversification of organisms and colonization of new ecological niches. Repeated bottlenecking of RNA viruses often leads to fitness losses due to the operation of Muller's ratchet. Herein we use vesicular stomatitis virus to determine the tran...

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書目詳細資料
發表在:J Virol
Principais autores: Novella, I S, Elena, S F, Moya, A, Domingo, E, Holland, J J
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 1995
主題:
在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188983/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7707510/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.5.2869-2872.1995
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