Size of genetic bottlenecks leading to virus fitness loss is determined by mean initial population fitness.

Genetic bottlenecks are important events in the genetic diversification of organisms and colonization of new ecological niches. Repeated bottlenecking of RNA viruses often leads to fitness losses due to the operation of Muller's ratchet. Herein we use vesicular stomatitis virus to determine the tran...

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Pubblicato in:	J Virol
Autori principali:	Novella, I S, Elena, S F, Moya, A, Domingo, E, Holland, J J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188983/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7707510/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.5.2869-2872.1995
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