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Encephalomyocarditis viruses with short poly(C) tracts are more virulent than their mengovirus counterparts.

We have constructed three cDNA clones of encephalomyocarditis virus strain R (EMCV-R) with poly(C) tracts of C4, C9, and C20. RNA transcribed from these cDNAs was infectious to HeLa cells, and the resultant viruses grew well in this system, albeit with plaque sizes that were proportional to the poly...

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:J Virol
Príomhchruthaitheoirí: Hahn, H, Palmenberg, A C
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: American Society for Microbiology (ASM) 1995
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188958/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7884926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.4.2697-2699.1995
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