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Encephalomyocarditis viruses with short poly(C) tracts are more virulent than their mengovirus counterparts.

We have constructed three cDNA clones of encephalomyocarditis virus strain R (EMCV-R) with poly(C) tracts of C4, C9, and C20. RNA transcribed from these cDNAs was infectious to HeLa cells, and the resultant viruses grew well in this system, albeit with plaque sizes that were proportional to the poly...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Hahn, H, Palmenberg, A C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188958/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7884926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.4.2697-2699.1995
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