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Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose

Conflicting reports have suggested that the silent information regulator 2 (SIR2) protein family employs NAD(+) to ADP-ribosylate histones [Tanny, J. C., Dowd, G. J., Huang, J., Hilz, H. & Moazed, D. (1999) Cell 99, 735–745; Frye, R. A. (1999) Biochem. Biophys. Res. Commun. 260, 273–279], deacetylat...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Tanner, Kirk G., Landry, Joseph, Sternglanz, Rolf, Denu, John M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18891/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11106374/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.250422697
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