Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose

Conflicting reports have suggested that the silent information regulator 2 (SIR2) protein family employs NAD(+) to ADP-ribosylate histones [Tanny, J. C., Dowd, G. J., Huang, J., Hilz, H. & Moazed, D. (1999) Cell 99, 735–745; Frye, R. A. (1999) Biochem. Biophys. Res. Commun. 260, 273–279], deacetylat...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Tanner, Kirk G., Landry, Joseph, Sternglanz, Rolf, Denu, John M.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2000
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18891/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11106374/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.250422697
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