Human immunodeficiency virus type 1 protease inhibitors irreversibly block infectivity of purified virions from chronically infected cells.

Synthetic peptide analog inhibitors of human immunodeficiency virus type 1 (HIV-1) protease were used to study the effects of inhibition of polyprotein processing on the assembly, structure, and infectivity of virions released from a T-cell line chronically infected with HIV-1. Inhibition of proteol...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Lambert, D M, Petteway, S R, McDanal, C E, Hart, T K, Leary, J J, Dreyer, G B, Meek, T D, Bugelski, P J, Bolognesi, D P, Metcalf, B W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188808/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1510424/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.5.982
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