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Human immunodeficiency virus type 1 protease inhibitors irreversibly block infectivity of purified virions from chronically infected cells.

Synthetic peptide analog inhibitors of human immunodeficiency virus type 1 (HIV-1) protease were used to study the effects of inhibition of polyprotein processing on the assembly, structure, and infectivity of virions released from a T-cell line chronically infected with HIV-1. Inhibition of proteol...

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Detalhes bibliográficos
Main Authors: Lambert, D M, Petteway, S R, McDanal, C E, Hart, T K, Leary, J J, Dreyer, G B, Meek, T D, Bugelski, P J, Bolognesi, D P, Metcalf, B W
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC188808/
https://ncbi.nlm.nih.gov/pubmed/1510424
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