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Essential Role of Survivin, an Inhibitor of Apoptosis Protein, in T Cell Development, Maturation, and Homeostasis

Survivin is an inhibitor of apoptosis protein that also functions during mitosis. It is expressed in all common tumors and tissues with proliferating cells, including thymus. To examine its role in apoptosis and proliferation, we generated two T cell–specific survivin-deficient mouse lines with dele...

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Detalhes bibliográficos
Main Authors: Xing, Zheng, Conway, Edward M., Kang, Chulho, Winoto, Astar
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887718/
https://ncbi.nlm.nih.gov/pubmed/14699085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031588
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