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Essential role for survivin in the proliferative expansion of progenitor and mature B cells()

Survivin is a member of the inhibitor of apoptosis family of proteins and a biomarker of poor prognosis in aggressive B cell non-Hodgkin’s lymphoma (B-NHL). In addition to its role in inhibition of apoptosis, survivin also regulates mitosis. Here, we show that deletion of survivin during early B cel...

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Bibliographic Details
Published in:J Immunol
Main Authors: Miletic, Ana V., Jellusova, Julia, Cato, Matthew H., Lee, Charlotte R., Baracho, Gisele V., Conway, Edward M., Rickert, Robert C.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761464/
https://ncbi.nlm.nih.gov/pubmed/26810226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501690
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