Gata-3 Induces T Helper Cell Type 2 (Th2) Cytokine Expression and Chromatin Remodeling in Committed Th1 Cells

Committed T helper type 1 (Th1) and Th2 effector cells, resulting from chronic antigenic stimulation in interleukin (IL)-12 and IL-4, are implicated in the pathology of autoimmune and allergic diseases. Committed Th1 cells cannot be induced to change their cytokine profiles in response to antigenic...

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Autors principals: Lee, Hyun Jun, Takemoto, Naofumi, Kurata, Hirokazu, Kamogawa, Yumiko, Miyatake, Shoichiro, O'Garra, Anne, Arai, Naoko
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2000
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887713/
https://ncbi.nlm.nih.gov/pubmed/10880531
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