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A genome-wide approach to identify genetic variants that contribute to etoposide-induced cytotoxicity

Large interindividual variance has been observed in sensitivity to drugs. To comprehensively decipher the genetic contribution to these variations in drug susceptibility, we present a genome-wide model using human lymphoblastoid cell lines from the International HapMap consortium, of which extensive...

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Detalhes bibliográficos
Main Authors: Huang, R. Stephanie, Duan, Shiwei, Bleibel, Wasim K., Kistner, Emily O., Zhang, Wei, Clark, Tyson A., Chen, Tina X., Schweitzer, Anthony C., Blume, John E., Cox, Nancy J., Dolan, M. Eileen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887589/
https://ncbi.nlm.nih.gov/pubmed/17537913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703736104
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