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Evidence that tetracycline analogs whose primary target is not the bacterial ribosome cause lysis of Escherichia coli.

The modes of action of atypical tetracyclines that do not directly inhibit bacterial protein synthesis were investigated. The analogs tested, chelocardin, anhydrotetracycline, 6-thiatetracycline, anhydrochlortetracycline, and 4-epi-anhydrochlortetracycline, were bactericidal and caused the lysis of...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Oliva, B, Gordon, G, McNicholas, P, Ellestad, G, Chopra, I
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188751/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1510413/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.5.913
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