Evidence that tetracycline analogs whose primary target is not the bacterial ribosome cause lysis of Escherichia coli.

The modes of action of atypical tetracyclines that do not directly inhibit bacterial protein synthesis were investigated. The analogs tested, chelocardin, anhydrotetracycline, 6-thiatetracycline, anhydrochlortetracycline, and 4-epi-anhydrochlortetracycline, were bactericidal and caused the lysis of...

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Bibliografische gegevens

Gepubliceerd in:	Antimicrob Agents Chemother
Hoofdauteurs:	Oliva, B, Gordon, G, McNicholas, P, Ellestad, G, Chopra, I
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 1992
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188751/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1510413/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.5.913
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