Evidence that tetracycline analogs whose primary target is not the bacterial ribosome cause lysis of Escherichia coli.
The modes of action of atypical tetracyclines that do not directly inhibit bacterial protein synthesis were investigated. The analogs tested, chelocardin, anhydrotetracycline, 6-thiatetracycline, anhydrochlortetracycline, and 4-epi-anhydrochlortetracycline, were bactericidal and caused the lysis of...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Principais autores: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1992
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188751/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1510413/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.5.913 |
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