Comparative Genomic Hybridization of Human Malignant Gliomas Reveals Multiple Amplification Sites and Nonrandom Chromosomal Gains and Losses

Nine human malignant gliomas (2 astrocytomas grade III and 7 glioblastomas) were analyzed using comparative genomic hybridization (CGH). In addition to the amplification of the EGFR gene at 7p12 in 4 of 9 cases, six new amplification sites were mapped to 1q32, 4q12, 7q21.1, 7q21.2-3, 12p, and 22q12....

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Detalhes bibliográficos
Main Authors: Schròck, Evelin, Thiel, Gundula, Lozanova, Tanka, du Manoir, Stanislas, Meffert, Marie-Christine, Jauch, Anna, Speicher, Michael R., Nürnberg, Peter, Vogel, Siegfried, Janisch, Werner, Donis-Keller, Helen, Ried, Thomas, Witkowski, Regine, Cremer, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887475/
https://ncbi.nlm.nih.gov/pubmed/8203461
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