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Centrosome Amplification and Instability Occurs Exclusively in Aneuploid, But Not in Diploid Colorectal Cancer Cell Lines, and Correlates With Numerical Chromosomal Aberrations

Measurement of the nuclear DNA content allows classification of human cancers as either diploid or aneuploid. To gain further insight into mechanisms of aneuploidy, we compared the cytogenetic profile of mismatch-repair–deficient diploid versus mismatch-repair–proficient aneuploid colorectal carcino...

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Detalhes bibliográficos
Publicado no:Genes Chromosomes Cancer
Main Authors: Ghadimi, B. Michael, Sackett, Dan L., Difilippantonio, Michael J., Schröck, Evelin, Neumann, Thomas, Jauho, Annukka, Auer, Gert, Ried, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721570/
https://ncbi.nlm.nih.gov/pubmed/10612807
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