Expression of the apoptosis-suppressing protein bcl-2, in neuroblastoma is associated with unfavorable histology and N-myc amplification.

Survival rate in neuroblastoma, a tumor of post-ganglionic sympathetic neuroblasts, correlates with disease stage, tumor histology, and N-myc gene amplification. N-myc amplification is associated with rapid tumor progression and poor survival, but is not present in all cases of poor prognosis neurob...

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Bibliographic Details
Main Authors: Castle, V. P., Heidelberger, K. P., Bromberg, J., Ou, X., Dole, M., Nuñez, G.
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887263/
https://ncbi.nlm.nih.gov/pubmed/8256847
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